Design and Optimization of Self Nano-Emulsifying Drug Delivery System Containing a New Anti-inflamatory Agent Pentagamavunon-0
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چکیده
منابع مشابه
Design, Development and In Vitro Characterization of Self Emulsifying Drug Delivery System for Irbesartan
The objectives of present investigations were to optimize concentration of oil, surfactant and cosurfactant by pseudoternary phase diagrams and to develop a stable formulation of self emulsifying drug delivery system (SEDDS) in order to enhance the dissolution rate of poorly soluble Irbesartan (IBS) by SEDDS. Pseudoternary phase diagrams were constructed to identify the self emulsifying region....
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Purpose: To prepare and characterize tablets loaded with self-nanoemulsifying drug delivery system (SNEDDS) containing docetaxel (DTL). Method: SNEDDS of docetaxel were prepared using various oils, surfactants, co-surfactant and solvents to improve the dissolution rate and bioavailability of the poorly water-soluble chemotherapeutic agent. The SNEDDS components were preliminarily screened for t...
متن کاملDevelopment, Characterization and Optimization of Ibuprofen Self-emulsifying Drug Delivery System Applying Face Centered Experimental Design
Ibuprofen (IB) a NSAID, has poor dissolution and many gastrointestinal side effects. Self-Emulsifying drug delivery system (SEDDS) has proved its efficacy to improve the solubility and dissolution of many lipophilic drugs and improve their characteristics. The objectives of this study were to develop, optimize and characterize a IBSEDDS applying Face Centered Experimental Design (FCED). The met...
متن کاملdesign, development and in vitro characterization of self emulsifying drug delivery system for irbesartan
the objectives of present investigations were to optimize concentration of oil, surfactant and cosurfactant by pseudoternary phase diagrams and to develop a stable formulation of self emulsifying drug delivery system (sedds) in order to enhance the dissolution rate of poorly soluble irbesartan (ibs) by sedds. pseudoternary phase diagrams were constructed to identify the self emulsifying region....
متن کاملRecent advances in self emulsifying drug delivery system - A review
Self-emulsifying drug delivery systems (SEDDS) are usually used to improve the bioavailability of hydrophobic drugs. Approximately 40% of new chemical entities exhibit poor aqueous solubility and present a major challenge to modern drug delivery system, because of their low bioavailability. From time to time many workers have claimed various rational applications of Self-emulsifying formulation...
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ژورنال
عنوان ژورنال: Indonesian Journal of Chemistry
سال: 2017
ISSN: 2460-1578,1411-9420
DOI: 10.22146/ijc.22640